Mouse Anti-GLS2 Recombinant Antibody (585CT26-3-1) (CBMAB-G3897-LY)

Name: Mouse Anti-GLS2 Recombinant Antibody (585CT26-3-1)
SKU: CBMAB-G3897-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

585CT26-3-1

Application

ELISA, WB

Immunogen

lgA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the Central region of human lgA

Specificity

Human

Antibody Isotype

IgM

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

glutaminase 2 (liver, mitochondrial)

Introduction

The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

Entrez Gene ID

27165

UniProt ID

Q9UI32

Alternative Names

Glutaminase 2; Glutaminase 2 (Liver; Mitochondrial); L-Glutamine Amidohydrolase; EC 3.5.1.2; GLS; GA; Glutaminase Liver Isoform; Mitochondrial; Phosphate-Activated Glutaminase;

Function

Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.

Biological Process

Cellular amino acid metabolic process Source: ProtInc
Glutamate biosynthetic process Source: GO_Central
Glutamine catabolic process Source: GO_Central
Reactive oxygen species metabolic process Source: MGI
Regulation of apoptotic process Source: MGI

Cellular Location

Mitochondrion

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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