Rabbit Anti-GLUD1 Recombinant Antibody (G3910) (V2LY-1225-LY1545)
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Basic Information
| Application | Note |
| WB | 1:1,000-1:2,000 |
| IF(ICC) | 1:50-1:200 |
| IHC | 1:100-1:200 |
| FC | 1:20-1:100 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays a role in insulin homeostasis (PubMed:9571255, PubMed:11297618).
May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
Glutamate catabolic process Source: UniProtKB
Glutamine metabolic process Source: UniProtKB
Positive regulation of insulin secretion Source: BHF-UCL
Substantia nigra development Source: UniProtKB
Tricarboxylic acid metabolic process Source: UniProtKB
Familial hyperinsulinemic hypoglycemia [MIM:256450], also referred to as congenital hyperinsulinism, nesidioblastosis, or persistent hyperinsulinemic hypoglycemia of infancy (PPHI), is the most common cause of persistent hypoglycemia in infancy and is due to defective negative feedback regulation of insulin secretion by low glucose levels. In HHF6 elevated oxidation rate of glutamate to alpha-ketoglutarate stimulates insulin secretion in the pancreatic beta cells, while they impair detoxification of ammonium in the liver.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
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Mouse Anti-GLUD1 Recombinant Antibody (CBLG1-1320) (CAT#: CBMAB-G3912-LY)
Rat Anti-GLUD1 Recombinant Antibody (CBLG1-1321) (CAT#: V2LY-1225-LY1544)
Mouse Anti-GLUD1 Recombinant Antibody (CBLG1-1321) (CAT#: CBMAB-G3913-LY)
Rabbit Anti-GLUD1 Recombinant Antibody (D9F7P) (CAT#: CBMAB-G3910-LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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