Sign in or Register   Sign in or Register
  |  

Mouse Anti-GNG7 Recombinant Antibody (1C11-1B3) (CBMAB-G4155-LY)

This product is antibody recognizes GNG7. The antibody 1C11-1B3 immunoassay techniques such as: ELISA, WB.
See all GNG7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C11-1B3
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
guanine nucleotide binding protein (G protein), gamma 7
Entrez Gene ID
2788
UniProt ID
O60262
Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity).
Biological Process
G protein-coupled receptor signaling pathway Source: GO_Central
Regulation of G protein-coupled receptor signaling pathway Source: ProtInc
Cellular Location
Cell membrane

Fang, C., Zhong, R., Qiu, C., & Zou, B. B. (2022). The prognostic value of GNG7 in colorectal cancer and its relationship with immune infiltration. Frontiers in Genetics, 13.

Zou, C., Lv, X., Wei, H., Wu, S., Song, J., Tang, Z., ... & Ai, Y. (2022). Long non-coding RNA LINC00472 inhibits oral squamous cell carcinoma via miR-4311/GNG7 axis. Bioengineered, 13(3), 6371-6382.

Zheng, H., Tian, H., Yu, X., Ren, P., & Yang, Q. (2021). G protein gamma 7 suppresses progression of lung adenocarcinoma by inhibiting E2F transcription factor 1. International Journal of Biological Macromolecules, 182, 858-865.

Zhao, X., Zhang, X. C., Zang, K., & Yu, Z. H. (2021). MicroRNA miR-19b-3p mediated G protein γ subunit 7 (GNG7) loss contributes lung adenocarcinoma progression through activating Hedgehog signaling. Bioengineered, 12(1), 7849-7858.

Lai, W., & Yu, L. (2021). Elevated MicroRNA 183 impairs trophoblast migration and invasiveness by downregulating FOXP1 expression and elevating GNG7 expression during preeclampsia. Molecular and Cellular Biology, 41(1), e00236-20.

Brunori, G., Pelletier, O. B., Stauffer, A. M., & Robishaw, J. D. (2021). Selective manipulation of G-protein γ7 subunit in mice provides new insights into striatal control of motor behavior. Journal of Neuroscience, 41(44), 9065-9081.

Xu, S., Zhang, H., Liu, T., Chen, Y., He, D., & Li, L. (2019). G Protein γ subunit 7 loss contributes to progression of clear cell renal cell carcinoma. Journal of cellular physiology, 234(11), 20002-20012.

Lai, W. S., & Ding, Y. L. (2019). GNG7 silencing promotes the proliferation and differentiation of placental cytotrophoblasts in preeclampsia rats through activation of the mTOR signaling pathway. International Journal of Molecular Medicine, 43(5), 1939-1950.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GNG7 Recombinant Antibody (1C11-1B3)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare