E. coli-derived recombinant human GSK-3 beta, Met1-Thr420, Accession # P49841
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
Glycogen Synthase Kinase 3 Beta; EC 184.108.40.206; Serine/Threonine-Protein Kinase GSK3B; EC 220.127.116.11; GSK-3 Beta; EC 2.7.11;