Mouse Anti-GUCA1C Recombinant Antibody (CBLG1-282) (CBMAB-G0935-LY)

This product is antibody recognizes GUCA1C. The antibody CBLG1-282 immunoassay techniques such as: ELISA, IP, WB.
See all GUCA1C antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBLG1-282

Antibody Isotype

IgG2a, κ

Application

ELISA, IP, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

guanylate cyclase activator 1C

Entrez Gene ID

9626

UniProt ID

O95843

Alternative Names

GCAP3

Function

Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca2+-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.

Biological Process

Signal transduction Source: ProtInc
Visual perception Source: ProtInc

Cellular Location

Photoreceptor disc membrane

References

Souzeau, E., Weisschuh, N., Craig, J. E., Pasutto, F., & Koch, K. W. (2021). An assessment of GUCA1C variants in primary congenital glaucoma. Genes, 12(3), 359.

Morales-Cámara, S., Alexandre-Moreno, S., Bonet-Fernández, J. M., Atienzar-Aroca, R., Aroca-Aguilar, J. D., Ferre-Fernández, J. J., ... & Escribano, J. (2020). Role of GUCA1C in primary congenital glaucoma and in the retina: functional evaluation in zebrafish. Genes, 11(5), 550.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
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Second antibody and isotype control

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