Mouse Anti-GUCA2A Recombinant Antibody (7A8) (CBMAB-G5770-LY)

Name: Mouse Anti-GUCA2A Recombinant Antibody (7A8)
SKU: CBMAB-G5770-LY
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Human

Clone

7A8

Antibody Isotype

IgG

Application

ELISA, WB

Basic Information

Immunogen

GUCA2A (NP_291031.2, aa1-115) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

guanylate cyclase activator 2A (guanylin)

Entrez Gene ID

2980

UniProt ID

Q02747

Alternative Names

GCAP-I; GUCA2; STARA

Function

Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.

Cellular Location

Secreted

More Infomation

References

Hoffsten, A., Lilja, H. E., Mobini-Far, H., Sindelar, R., & Markasz, L. (2023). Paneth cell proteins DEFA6 and GUCA2A as tissue markers in necrotizing enterocolitis. European Journal of Pediatrics, 182(6), 2775-2784.

Zhang, H., Du, Y., Wang, Z., Lou, R., Wu, J., & Feng, J. (2019). Integrated analysis of oncogenic networks in colorectal cancer identifies GUCA2A as a molecular marker. Biochemistry Research International, 2019.

Bashir, B., Merlino, D. J., Rappaport, J. A., Gnass, E., Palazzo, J. P., Feng, Y., ... & Waldman, S. A. (2019). Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia. Human pathology, 87, 103-114.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-GUCA2A Recombinant Antibody (MAK-L-G-11)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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