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Mouse Anti-HAGH (AA 279-308 ) Monoclonal Antibody (CBFYH-3011) (CBMAB-H1549-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-3011
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
KLH conjugated synthetic peptide between 279-308 amino acids from the C-terminal region of human HAGH
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 279-308

Target

Full Name
hydroxyacylglutathione hydrolase
Introduction
The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
3029
UniProt ID
Q16775
Alternative Names
Hydroxyacylglutathione Hydrolase; Glyoxalase II; EC 3.1.2.6; Glx II; HAGH1; GLO2
Function
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
Biological Process
Glutathione biosynthetic process Source: UniProtKB
Glutathione metabolic process Source: GO_Central
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione Source: InterPro
Cellular Location
Isoform 1: Mitochondrion matrix
Isoform 2: Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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