Mouse Anti-HAPLN4 (AA 30-135) Recombinant Antibody (CBFYH-0694) (CBMAB-H1582-FY)

Name: Mouse Anti-HAPLN4 (AA 30-135) Recombinant Antibody (CBFYH-0694)
SKU: CBMAB-H1582-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-0694

Application

Immunogen

Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG3, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 30-135

More Infomation

Target

Full Name

hyaluronan and proteoglycan link protein 4

Introduction

HAPLN4 (Hyaluronan And Proteoglycan Link Protein 4) is a Protein Coding gene. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include extracellular matrix structural constituent and hyaluronic acid binding. An important paralog of this gene is HAPLN1.

Entrez Gene ID

404037

UniProt ID

Q86UW8

Alternative Names

Hyaluronan And Proteoglycan Link Protein 4; Brain Link Protein 2; BRAL2; KIAA1926

Function

Binds to hyaluronic acid and may be involved in formation of the extracellular matrix.

Biological Process

Cell adhesion Source: InterPro
Central nervous system development Source: GO_Central
Skeletal system development Source: GO_Central

Cellular Location

Extracellular matrix

Sucha, P., Chmelova, M., Kamenicka, M., Bochin, M., Oohashi, T., & Vargova, L. (2020). The effect of Hapln4 link protein deficiency on extracellular space diffusion parameters and perineuronal nets in the auditory system during aging. Neurochemical Research, 45, 68-82.

Liu, W., Geng, L., & Chen, Y. (2018). MiR-19b alleviates MPP+-induced neuronal cytotoxicity via targeting the HAPLN4/MAPK pathway in SH-SY5Y cells. RSC advances, 8(19), 10706-10714.

Edamatsu, M., Miyano, R., Fujikawa, A., Fujii, F., Hori, T., Sakaba, T., & Oohashi, T. (2018). Hapln4/Bral2 is a selective regulator for formation and transmission of GABA ergic synapses between Purkinje and deep cerebellar nuclei neurons. Journal of Neurochemistry, 147(6), 748-763.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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