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Mouse Anti-HAUS8 Recombinant Antibody (CBFYH-2856) (CBMAB-H1610-FY)

This product is mouse antibody that recognizes HAUS8. The antibody CBFYH-2856 can be used for immunoassay techniques such as: WB.
See all HAUS8 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-2856
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
HAUS Augmin Like Complex Subunit 8
Introduction
HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).
Entrez Gene ID
UniProt ID
Alternative Names
HAUS Augmin Like Complex Subunit 8; HEC1/NDC80-Interacting Centrosome-Associated Protein 1; HEC1/NDC80 Interacting, Centrosome Associated 1; Sarcoma Antigen NY-SAR-48; HICE1; Hec1-Interacting And Centrosome-Associated 1; HAUS Augmin-Like Complex Subunit 8; NY-SAR-48; DGT4
Function
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Biological Process
Cell division Source: UniProtKB-KW
Centrosome cycle Source: UniProtKB
Spindle assembly Source: UniProtKB
Cellular Location
Cytoplasm; Centrosome; Spindle; Spindle pole. During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively. Localizes to mitotic spindle microtubules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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