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Mouse Anti-HAVCR2 Recombinant Antibody (CBYJT-1354) (CBMAB-T0373-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to HAVCR2 (Hepatitis A Virus Cellular Receptor 2). The antibody can be used for immunoassay techniques, such as IHC, IHC-P.
See all HAVCR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1354
Antibody Isotype
IgG1
Application
IHC, IHC-P

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 22-202 of human HAVCR2 (NP_116171) produced in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 22-202

Target

Full Name
Hepatitis A Virus Cellular Receptor 2
Introduction
HAVCR2 belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. It is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Entrez Gene ID
UniProt ID
Alternative Names
Hepatitis A Virus Cellular Receptor 2; T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3; T-Cell Immunoglobulin Mucin Family Member 3; T-Cell Immunoglobulin Mucin Receptor 3; T-Cell Membrane Protein 3; HAVcr-2; TIMD-3; Tim-3
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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