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Rat Anti-HAVCR2 Recombinant Antibody (8B.2C12) (CBMAB-C9049-LY)

This product is antibody recognizes HAVCR2. The antibody 8B.2C12 immunoassay techniques such as: FC, IHC, IP.
See all HAVCR2 antibodies
Published Data
Fig.1 PD-1 and Tim-3 expression in TILs.
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Fig.2 The expression of Tim-3 and IFN-γ was analyzed in NK cells from septic mice at 24 h after LPS injection.
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Fig.3 Effect of targeting the Tim-3 and PD-1 signaling pathways on the development of urogenital tract gross pathology.
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Summary

Host Animal
Rat
Specificity
Mouse
Clone
8B.2C12
Antibody Isotype
IgG1, κ
Application
FC, IHC, IP

Basic Information

Specificity
Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Hepatitis A Virus Cellular Receptor 2
Introduction
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Entrez Gene ID
171285
UniProt ID
Q8VIM0
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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