Rabbit Anti-HDAC1 (Phospho-Ser421) Recombinant Antibody (EG1492) (CBMAB-EN1783-LY)

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Basic Information

Host Animal
Rabbit
Clone
EG1492
Application
WB: 1:500~1:1000 ELISA: 1:5000
Immunogen
The antibody was produced against synthesized phosphopeptide derived from human HDAC1 around the phosphorylation site of serine 421 (E-F-SP-D-S).
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
histone deacetylase 1
Introduction
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Entrez Gene ID
Human3065
Mouse433759
UniProt ID
HumanQ13547
MouseO09106
Alternative Names
HD1; RPD3; KDAC1; GON-10; RPD3L1
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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