Mouse Anti-HEMGN (AA 260-484) Recombinant Antibody (CBFYH-0925) (CBMAB-H1859-FY)

This product is mouse antibody that recognizes HEMGN. The antibody CBFYH-0925 can be used for immunoassay techniques such as: IHC-P.
See all HEMGN antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYH-0925

Antibody Isotype

IgG1

Application

IHC-P

Basic Information

Immunogen

Human recombinant protein fragment corresponding to amino acids 260-484 of human HEMGN produced in E. coli.

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 260-484

Target

Full Name

Hemogen

Introduction

HEMGN (Hemogen) is a Protein Coding gene. Diseases associated with HEMGN include Isolated Cleft Lip.

Entrez Gene ID

55363

UniProt ID

Q9BXL5

Alternative Names

Hemogen; Erythroid Differentiation-Associated Gene Protein; Negative Differentiation Regulator Protein; Hemopoietic Gene Protein; EDAG-1; EDAG; NDR; CT155

Function

Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).

Biological Process

Cell differentiation Source: UniProtKB-KW
Regulation of osteoblast differentiation Source: GO_Central

Cellular Location

Nucleus

References

Jiang, Y., Yu, L., Hu, Q., Kang, Y., You, J., Huang, C., ... & Chen, L. (2023). Cancer/testis antigen HEMGN correlated with immune infiltration serves as a prognostic biomarker in lung adenocarcinoma. Molecular Immunology, 153, 226-237.

Zhao, K., Liu, J. F., Zhu, Y. X., Dong, X. M., Yin, R. H., Liu, X., ... & Li, C. Y. (2022). Hemgn Protects Hematopoietic Stem and Progenitor Cells Against Transplantation Stress Through Negatively Regulating IFN‐γ Signaling. Advanced Science, 9(5), 2103838.

Li, Z., Huang, X., Liu, A., Xu, J., Lai, J., Guan, H., & Ma, J. (2021). Circ_PSD3 promotes the progression of papillary thyroid carcinoma via the miR-637/HEMGN axis. Life Sciences, 264, 118622.

Wu, Z., Wen, Y., Fan, G., He, H., Zhou, S., & Chen, L. (2021). HEMGN and SLC2A1 might be potential diagnostic biomarkers of steroid-induced osteonecrosis of femoral head: study based on WGCNA and DEGs screening. BMC Musculoskeletal Disorders, 22, 1-12.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-HEMGN (AA 260-484) Recombinant Antibody (CBFYH-0925)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-HEMGN (AA 260-484) Recombinant Antibody (CBFYH-2851)

Mouse Anti-HEMGN (AA 260-484) Recombinant Antibody (CBFYE-1459)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: