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Mouse Anti-HINFP Antibody (1A1) (CBMAB-0473-YC)

Provided herein are mouse monoclonal antibodies against Human HINFP. The antibody clone 1A1 can be used for immunoassay techniques, such as IP and MA.
See all HINFP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A1
Antibody Isotype
IgG2b
Application
IP, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
HINFP
Introduction
HINFP (histone h4 transcription factor) is a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex. HINFP plays a role in DNA methylation and transcription repression.
Entrez Gene ID
25988
UniProt ID
Q9BQA5
Alternative Names
HiNF-P; MIZF; ZNF743
Function
Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
Biological Process
Anatomical structure development Source: GO_Central
DNA damage checkpoint signaling Source: UniProtKB
DNA repair Source: UniProtKB
Establishment of protein localization Source: UniProtKB
G1/S transition of mitotic cell cycle Source: UniProtKB
In utero embryonic development Source: UniProtKB
Myoblast differentiation Source: UniProtKB
Negative regulation of gene expression Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of gene expression Source: UniProtKB
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: ARUK-UCL
Regulation of gene expression Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Regulation of transcription involved in G1/S transition of mitotic cell cycle Source: UniProtKB
Transcription, DNA-templated Source: Ensembl
Cellular Location
Nucleus. Associated with discrete nuclear foci.
PTM
Ubiquitinated. Ubiquitination may lead to proteasome-mediated degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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