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Mouse Anti-HIRIP3 (AA 447-555) Recombinant Antibody (CBFYH-1139) (CBMAB-H2096-FY)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-1139
Antibody Isotype
IgG1, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa447-555 from HIRIP3 with GST tag. MW of the GST tag alone is 26kD.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 447-555

Target

Full Name
HIRA interacting protein 3
Introduction
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Entrez Gene ID
UniProt ID
Alternative Names
HIRA Interacting Protein 3; HIRA-Interacting Protein 3
Function
May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.
Biological Process
Chromatin assembly or disassembly Source: ProtInc
Cellular Location
Nucleus. Nuclear throughout the cell cycle and is excluded from condensed chromatin during mitosis.
PTM
Phosphorylated by CK2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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