Mouse Anti-HMGXB4 Antibody (1B3) (CBMAB-0489-YC)

Provided herein are mouse monoclonal antibodies against Human HMGXB4. The antibody clone 1B3 can be used for immunoassay techniques, such as IP, WB and MA.
See all HMGXB4 antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

1B3

Antibody Isotype

IgG2b

Application

IP, WB, MA

Basic Information

Immunogen

Recombinant protein

Specificity

Human

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

HMGXB4

Introduction

HMGXB4 (HMG box domain containing 4) is one of nonhistone chromosomal proteins, which has chromatin binding activity. Diseases associated with HMGXB4 include Spherocytosis, Type 4.

Entrez Gene ID

10042

UniProt ID

Q9UGU5

Alternative Names

HMG2L1; THC211630

Function

Negatively regulates Wnt/beta-catenin signaling during development.

Biological Process

Endosome to lysosome transport Source: UniProtKB
Negative regulation of Wnt signaling pathway Source: UniProtKB
Wnt signaling pathway Source: UniProtKB-KW

Cellular Location

Nucleus

References

Devaraj, A., Singh, M., Narayanavari, S. A., Yong, G., Chen, J., Wang, J., ... & Izsvák, Z. (2023). HMGXB4 targets Sleeping Beauty transposition to germinal stem cells. International Journal of Molecular Sciences, 24(8), 7283.

He, X., Dong, K., Shen, J., Hu, G., Liu, J., Kang, X., ... & Zhou, J. (2021). Deficiency of the novel high mobility group protein HMGXB4 protects against systemic inflammation-induced endotoxemia in mice. Proceedings of the National Academy of Sciences, 118(7), e2021862118.

He, X., Dong, K., Shen, J., Osman, I., Hu, G., & Zhou, J. (2020). The Novel High Mobility Group Protein Hmgxb4 Promotes Neointimal Formation in Response to Arterial Injury. Circulation, 142(Suppl_3), A15691-A15691.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-HMGXB4 Antibody (1B3)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-HMGXB4 Monoclonal Antibody (CBFYH-3170)

Mouse Anti-HMGXB4 Monoclonal Antibody (CBFYH-3171)

Mouse Anti-HMGXB4 Recombinant Antibody (CBFYH-1560)

Mouse Anti-HMGXB4 (AA 1-348) Recombinant Antibody (CBFYH-1555)

Mouse Anti-HMGXB4 (AA 1-74) Recombinant Antibody (CBFYH-1558)

Mouse Anti-HMGXB4 Monoclonal Antibody (CBFYH-3168)

Mouse Anti-HMGXB4 Recombinant Antibody (3B4)

Mouse Anti-HMGXB4 (AA 1-348) Recombinant Antibody (CBFYH-1556)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: