Mouse Anti-HSDL2 Recombinant Antibody (CBFYH-2027) (CBMAB-H3042-FY)

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Basic Information

Host Animal
Mouse
Clone
CBFYH-2027
Application
ELISA, IF, IP
Immunogen
Human HSDL2
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Hydroxysteroid Dehydrogenase Like 2
Introduction
HSDL2 (Hydroxysteroid Dehydrogenase Like 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity. An important paralog of this gene is DHRS1.
Entrez Gene ID
UniProt ID
Alternative Names
Hydroxysteroid Dehydrogenase Like 2; Short Chain Dehydrogenase/Reductase Family 13C Member 1; C9orf99; SDR13C1; Short Chain Dehydrogenase/Reductase Family 13C, Member 1; Hydroxysteroid Dehydrogenase-Like Protein 2
Function
Has apparently no steroid dehydrogenase activity.
Cellular Location
Peroxisome

Liu, W. B., Wang, H. L., Chen, L., Tang, B., Ke, G., Wang, S., ... & Lyu, D. L. (2022). Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression. Chinese Medicine, 17(1), 1-11.

Yang, Y., Han, A., Wang, X., Yin, X., Cui, M., & Lin, Z. (2021). Lipid metabolism regulator human hydroxysteroid dehydrogenase‐like 2 (HSDL2) modulates cervical cancer cell proliferation and metastasis. Journal of Cellular and Molecular Medicine, 25(10), 4846-4859.

Han, A., Xu, R., Liu, Y., Yin, X., Lin, Z., & Yang, W. (2021). HSDL2 acts as a promoter in pancreatic cancer by regulating cell proliferation and lipid metabolism. OncoTargets and therapy, 435-444.

Shi, Y., Mao, Z., Huang, Y., Sun, Y., Cao, Q., Yin, X., ... & Zhang, Q. (2020). Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression. Bioscience Reports, 40(4), BSR20200348.

Dong, B., Yang, Y., Han, A., Zhang, S., Lin, Z., Wang, Y., & Piao, J. (2019). Ectopic expression of HSDL2 is related to cell proliferation and prognosis in breast cancer. Cancer Management and Research, 6531-6542.

Zeng, J., Ma, X., Wang, J., Liu, R., Shao, Y., Hou, Y., ... & Fang, Y. (2019). Down-regulated HSDL2 expression suppresses cell proliferation and promotes apoptosis in papillary thyroid carcinoma. Bioscience Reports, 39(6), BSR20190425.

Jia, L. H., Hu, M. D., Liu, Y., Xiong, X., Wang, W. J., Wang, J. G., & Li, Q. G. (2019). HSDL2 promotes bladder cancer growth in vitro and in vivo. International Journal of Medical Sciences, 16(5), 654.

Zhang, D. Y., Liu, Z., Lu, Z., Sun, W. L., Ma, X., Zhang, P., ... & Cui, P. Y. (2018). Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma. OncoTargets and therapy, 7133-7142.

Sun, Q., Zhang, Y., Su, J., Li, T., & Jiang, Y. (2018). Role of hydroxysteroid dehydrogenase-like 2 (HSDL2) in human ovarian cancer. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 24, 3997.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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