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Mouse Anti-IDI1 Recombinant Antibody (6G10) (CBMAB-A4223-LY)

The product is antibody recognizes IDI1. The antibody 6G10 immunoassay techniques such as: WB, ELISA.
See all IDI1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6G10
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
IDI1 (NP_004499, 175 a.a. ~ 283 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
isopentenyl-diphosphate delta isomerase 1
Introduction
IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq]
Entrez Gene ID
3422
UniProt ID
Q13907
Alternative Names
IPP1; IPPI1
Function
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Biological Process
Cholesterol biosynthetic process Source: UniProtKB-KW
Dimethylallyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Isopentenyl diphosphate biosynthetic process Source: GO_Central
Isoprenoid biosynthetic process Source: UniProtKB
Cellular Location
Peroxisome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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