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Mouse Anti-IDI2 Recombinant Antibody (1C11) (CBMAB-I0242-YY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1C11
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
isopentenyl-diphosphate delta isomerase 2
Introduction
The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis.
Entrez Gene ID
91734
UniProt ID
Q9BXS1
Alternative Names
IPPI2
Function
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Biological Process
Cholesterol biosynthetic process Source: UniProtKB-KW
Dimethylallyl diphosphate biosynthetic process Source: UniProtKB-UniPathway
Isopentenyl diphosphate biosynthetic process Source: GO_Central
Isopentenyl diphosphate metabolic process Source: MGI
Isoprenoid biosynthetic process Source: UniProtKB
Cellular Location
Peroxisome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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