Mouse Anti-IGSF1 Recombinant Antibody (4C7) (CBMAB-A4304-LY)

Nikolaou, M., Vasilakis, I. A., Marinakis, N. M., Tilemis, F. N., Zellos, A., Lykopoulou, E., ... & Kanaka-Gantenbein, C. (2023). Hepatomegaly and fatty liver disease secondary to central hypothyroidism in combination with macrosomia as initial presentation of IGSF1 deficiency syndrome. Hormones, 1-6.

Fourneaux, R., Reynaud, R., Mougel, G., Castets, S., Bretones, P., Dauriat, B., ... & Saveanu, A. (2022). IGSF1 mutations are the most frequent genetic aetiology of thyrotropin deficiency. European Journal of Endocrinology, 187(6), 787-795.

Elizabeth, M. S., Hokken-Koelega, A., Visser, J. A., Joustra, S. D., & de Graaff, L. C. (2022). Case report: A detailed phenotypic description of patients and relatives with combined central hypothyroidism and growth hormone deficiency carrying IGSF1 mutations. Genes, 13(4), 623.

Brûlé, E., Silander, T. L., Wang, Y., Zhou, X., Bak, B., Groeneweg, S., & Bernard, D. J. (2022). IGSF1 deficiency leads to reduced TSH production independent of alterations in thyroid hormone action in male mice. Endocrinology, 163(8), bqac092.

Brûlé, E., Heinen, C. A., Smith, C. L., Schang, G., Li, Y., Zhou, X., ... & Bernard, D. J. (2021). IGSF1 does not regulate spermatogenesis or modify FSH synthesis in response to inhibins or activins. Journal of the Endocrine Society, 5(4), bvab023.

Bernard, D. J., Smith, C. L., & Brûlé, E. (2020). A tale of two proteins: betaglycan, IGSF1, and the continuing search for the inhibin B receptor. Trends in Endocrinology & Metabolism, 31(1), 37-45.

Joustra, S. D., Roelfsema, F., van Trotsenburg, A. P., Schneider, H. J., Kosilek, R. P., Kroon, H. M., ... & Schoenmakers, N. (2020). IGSF1 deficiency results in human and murine somatotrope neurosecretory hyperfunction. The Journal of Clinical Endocrinology & Metabolism, 105(3), e70-e84.

Guan, Y., Wang, Y., Bhandari, A., Xia, E., & Wang, O. (2019). IGSF1: A novel oncogene regulates the thyroid cancer progression. Cell Biochemistry and Function, 37(7), 516-524.

Roche, E. F., McGowan, A., Koulouri, O., Turgeon, M. O., Nicholas, A. K., Heffernan, E., ... & Schoenmakers, N. (2018). A novel IGSF 1 mutation in a large Irish kindred highlights the need for familial screening in the IGSF 1 deficiency syndrome. Clinical Endocrinology, 89(6), 813-823.

Bernard, D. J., Brûlé, E., Smith, C. L., Joustra, S. D., & Wit, J. M. (2018). From consternation to revelation: discovery of a role for IGSF1 in pituitary control of thyroid function. Journal of the Endocrine Society, 2(3), 220-231.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols