Rabbit Anti-IMP3 Recombinant Antibody (D6U2N) (CBMAB-CP1112-LY)

The product is antibody recognizes IMP3. The antibody D6U2N immunoassay techniques such as: WB.
See all IMP3 antibodies

Datasheet

Summary

Host Animal

Rabbit

Specificity

Human, Mouse, Monkey

Clone

D6U2N

Antibody Isotype

IgG

Application

Basic Information

Immunogen

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly572 of human IMP3 protein.

Specificity

Human, Mouse, Monkey

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

100 µg/ml BSA, 50% glycerol

Preservative

0.02% sodium azide

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

IMP3, U3 Small Nucleolar Ribonucleoprotein

Introduction

This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008]

Entrez Gene ID

Human	55272
Mouse	102462
Monkey	706202

UniProt ID

Human	Q9NV31
Mouse	Q921Y2
Monkey	G8F2V1

Alternative Names

IMP3; U3 Small Nucleolar Ribonucleoprotein

Function

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.

Biological Process

rRNA processingManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus, nucleolus

References

Martin-Morales, N., Padial-Molina, M., Tovar, I., De Araujo Farias, V., Hernández-Cortés, P., Ramirez-Moreno, E., ... & O’Valle Ravassa, F. J. (2023). IMP3 immunohistochemical expression is related with progression and metastases in xenografted and cutaneous melanomas. Pathobiology: Journal of Immunopathology, Molecular and Cellular Biology.

Khashman, B. M., Alwandawi, T. K., & Al-Jussani, G. N. (2022). Evaluation of Insulin-like Growth Factor II Mrna Binding Protein 3 (IMP3) Expression in A Group of Iraqi Women with Breast Cancer. HIV Nursing, 22(2), 471-473.

Albericio, G., Aguilar, S., Torán, J. L., Yañez, R., López, J. A., Vázquez, J., ... & Bernad, A. (2021). Comparative Proteomic Analysis of Nuclear and Cytoplasmic Compartments in Human Cardiac Progenitor Cells. Functional Evaluation of IL1A and IMP3.

Sweeney, J., Rao, R., Margolskee, E., Goyal, A., Heymann, J. J., & Siddiqui, M. T. (2018). Immunohistochemical staining for S100P, SMAD4, and IMP3 on cell block preparations is sensitive and highly specific for pancreatic ductal adenocarcinoma. Journal of the American Society of Cytopathology, 7(6), 318-323.

Burdelski, C., Jakani-Karimi, N., Jacobsen, F., Möller-Koop, C., Minner, S., Simon, R., ... & Wilczak, W. (2018). IMP3 overexpression occurs in various important cancer types and is linked to aggressive tumor features: A tissue microarray study on 8,877 human cancers and normal tissues. Oncology reports, 39(1), 3-12.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Rabbit Anti-IMP3 Recombinant Antibody (CBYY-I0526)

Mouse Anti-IMP3 Recombinant Antibody (A616)

Mouse Anti-IMP3 Recombinant Antibody (A617)

Mouse Anti-IMP3 Recombinant Antibody (1F1-E10-D11)

Mouse Anti-IMP3 Recombinant Antibody (A618)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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