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Rat Anti-ITGB4 Recombinant Antibody (308601) (CBMAB-C0935-LY)

This product is antibody recognizes ITGB4. The antibody 308601 immunoassay techniques such as: FC, IHC-F, WB.
Host Animal
Rat
Application
FC, IHC-F, WB
Immunogen
CHO-derived recombinant mouse Integrin beta 4/CD104 Asn29-Ser711
Antibody Isotype
IgG2a
Specificity
Mouse
Cross Reactivity
Mouse
Clone
308601
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Cat CBMAB-C0935-LY
Conjugates
Size
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