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Rabbit Anti-JAK2 Recombinant Antibody (18H11L8) (CBMAB-0071-WJ)

This product is a rabbit antibody that recognizes JAK2. The antibody 18H11L8 can be used for immunoassay techniques such as: ICC, IF, WB.
Host Species
Rabbit
Application
ICC, IF, WB
Immunogen
Peptide corresponding to human JAK2 (amino acid 1004-1012)
Antibody Isotype
IgG
Specificity
Human
Clone
18H11L8
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. Diseases associated with JAK2 include Thrombocythemia 3 and Polycythemia Vera. Among its related pathways are RET signaling and Oncogenic MAPK signaling. An important paralog of this gene is JAK3.
Alternative Name
JAK2; Janus kinase 2; tyrosine-protein kinase JAK2; JTK10; JAK-2; Janus kinase 2 (a protein tyrosine kinase); THCYT3
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0071-WJ
Conjugates
Size
Price $
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Second antibody and isotype control