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Mouse Anti-JRA Recombinant Antibody (G-7) (CBMAB-0361-WJ)

This product is a mouse antibody that recognizes JRA. The antibody G-7 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all JRA antibodies

Summary

Host Animal
Mouse
Specificity
Common fruit fly
Clone
G-7
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Common fruit fly
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Jun-related antigen
Introduction
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. Diseases associated with JUN include Sarcoma and Pertussis. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.
Entrez Gene ID
UniProt ID
Alternative Names
AP-1; AP1; c-Jun; CG2275; cJun; d-JRA; d-jun; d-Jun; D-jun; D-Jun; D-jun/Jra; dAP-1; dJra; dJRA; djun; dJun; dJUN; Djun; DJun; DJUN; dm-Jun; DM14; Dmel\CG2275; jra; JRA; jun; Jun; JUN; l(2)46Ef; l(2)IA109; l(2R)IA109; V
Function
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' (PubMed:1696724, PubMed:2116361).
Plays a role in dorsal closure (PubMed:9224723).
Biological Process
Chorion micropyle formationManual Assertion Based On ExperimentIMP:FlyBase
Dorsal appendage formationManual Assertion Based On ExperimentIMP:FlyBase
Dorsal closureManual Assertion Based On ExperimentIMP:FlyBase
Imaginal disc fusion, thorax closureManual Assertion Based On ExperimentIMP:FlyBase
JNK cascadeManual Assertion Based On ExperimentIMP:FlyBase
Multicellular organism agingManual Assertion Based On ExperimentIMP:FlyBase
Negative regulation of antimicrobial humoral responseManual Assertion Based On ExperimentIMP:FlyBase
Positive regulation of heart contractionManual Assertion Based On ExperimentIMP:FlyBase
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:FlyBase
R3/R4 cell fate commitmentManual Assertion Based On ExperimentTAS:FlyBase
Regulation of cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Synaptic assembly at neuromuscular junctionManual Assertion Based On ExperimentIGI:FlyBase
Wound healingManual Assertion Based On ExperimentHMP:FlyBase
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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