Mouse Anti-JRA Recombinant Antibody (G-7) (CBMAB-0361-WJ)

Name: Mouse Anti-JRA Recombinant Antibody (G-7)
SKU: CBMAB-0361-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

G-7

Application

WB, IP, IF, ELISA

Specificity

Common fruit fly

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Jun-related antigen

Introduction

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. Diseases associated with JUN include Sarcoma and Pertussis. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.

Entrez Gene ID

36057

UniProt ID

P18289

Alternative Names

AP-1; AP1; c-Jun; CG2275; cJun; d-JRA; d-jun; d-Jun; D-jun; D-Jun; D-jun/Jra; dAP-1; dJra; dJRA; djun; dJun; dJUN; Djun; DJun; DJUN; dm-Jun; DM14; Dmel\CG2275; jra; JRA; jun; Jun; JUN; l(2)46Ef; l(2)IA109; l(2R)IA109; V

Function

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' (PubMed:1696724, PubMed:2116361).
Plays a role in dorsal closure (PubMed:9224723).

Biological Process

Chorion micropyle formationManual Assertion Based On ExperimentIMP:FlyBase
Dorsal appendage formationManual Assertion Based On ExperimentIMP:FlyBase
Dorsal closureManual Assertion Based On ExperimentIMP:FlyBase
Imaginal disc fusion, thorax closureManual Assertion Based On ExperimentIMP:FlyBase
JNK cascadeManual Assertion Based On ExperimentIMP:FlyBase
Multicellular organism agingManual Assertion Based On ExperimentIMP:FlyBase
Negative regulation of antimicrobial humoral responseManual Assertion Based On ExperimentIMP:FlyBase
Positive regulation of heart contractionManual Assertion Based On ExperimentIMP:FlyBase
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:FlyBase
R3/R4 cell fate commitmentManual Assertion Based On ExperimentTAS:FlyBase
Regulation of cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Synaptic assembly at neuromuscular junctionManual Assertion Based On ExperimentIGI:FlyBase
Wound healingManual Assertion Based On ExperimentHMP:FlyBase

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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