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Rabbit Anti-KCNG2 Recombinant Antibody (EG1753) (CBMAB-EN2092-LY)

The product is antibody recognizes KCNG2. The antibody EG1753 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:5000.
See all KCNG2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1753
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:5000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human KCNG2.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
potassium voltage-gated channel modifier subfamily G member 2
Introduction
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization.
Entrez Gene ID
Human26251
Mouse240444
Rat307234
UniProt ID
HumanQ9UJ96
MouseF7A6P6
RatQ9QYU3
Alternative Names
KCNF2; KV6.2
Function
Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
Biological Process
Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportManual Assertion Based On ExperimentTAS:ProtInc
Protein homooligomerizationIEA:InterPro
Regulation of heart contractionManual Assertion Based On ExperimentTAS:ProtInc
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Cellular Location
Membrane
Topology
Cytoplasmic: 1-177
Helical: 178-198
Helical: 218-238
Helical: 253-273
Helical: 288-308
Cytoplasmic: 309-321
Helical: 322-342
Pore-forming: 357-377
Helical: 385-405
Cytoplasmic: 406-466
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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