Rabbit Anti-KCNG2 Recombinant Antibody (EG1753) (CBMAB-EN2092-LY)

Name: Rabbit Anti-KCNG2 Recombinant Antibody (EG1753)
SKU: CBMAB-EN2092-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1753

Application

WB: 1:500~1:1000 ELISA: 1:5000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human KCNG2.

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

potassium voltage-gated channel modifier subfamily G member 2

Introduction

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization.

Entrez Gene ID

Human	26251
Mouse	240444
Rat	307234

UniProt ID

Human	Q9UJ96
Mouse	F7A6P6
Rat	Q9QYU3

Alternative Names

KCNF2; KV6.2

Function

Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.

Biological Process

Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportManual Assertion Based On ExperimentTAS:ProtInc
Protein homooligomerizationIEA:InterPro
Regulation of heart contractionManual Assertion Based On ExperimentTAS:ProtInc
Regulation of ion transmembrane transportIEA:UniProtKB-KW

Cellular Location

Membrane

Topology

Cytoplasmic: 1-177
Helical: 178-198
Helical: 218-238
Helical: 253-273
Helical: 288-308
Cytoplasmic: 309-321
Helical: 322-342
Pore-forming: 357-377
Helical: 385-405
Cytoplasmic: 406-466

Sun, C., Li, N., Wang, Q. Q., Yan, L. Y., Ba, S. K., Zhang, S. S., ... & Liu, K. C. (2022). Whole genome sequencing identifies a deletion mutation in the unknown-functional KCNG2 from familial sick sinus syndrome. Physiological Genomics, 54(4), 141-152.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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