Rabbit Anti-KCNK15 Recombinant Antibody (EG1764) (CBMAB-EN2103-LY)

The product is antibody recognizes KCNK15. The antibody EG1764 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000.
See all KCNK15 antibodies

Datasheet

Summary

Host Animal

Rabbit

Specificity

Human

Clone

EG1764

Antibody Isotype

IgG

Application

WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Basic Information

Immunogen

The antibody was produced against synthesized peptide derived from internal of human KCNK15.

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Potassium Two Pore Domain Channel Subfamily K Member 15

Introduction

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

Entrez Gene ID

60598

UniProt ID

Q9H427

Alternative Names

Potassium Two Pore Domain Channel Subfamily K Member 15; Potassium Channel, Two Pore Domain Subfamily K, Member 15; Acid-Sensitive Potassium Channel Protein TASK-5; TWIK-Related Acid-Sensitive K(+) Channel 5; Two Pore Potassium Channel KT3.3; Two Pore K(+) Channel KT3.3; TASK5; Potassium Channel, Subfamily K, Member 15; Potassium Channel, Subfamily K, Member 14;

Function

Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.

Biological Process

Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Stabilization of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-8
Helical: 9-29
Pore-forming: 80-101
Helical: 108-128
Cytoplasmic: 129-158
Helical: 159-179
Pore-forming: 189-209
Helical: 223-243
Cytoplasmic: 244-330

References

He, Y., Yue, H., Cheng, Y., Ding, Z., Xu, Z., Lv, C., ... & Chen, C. (2021). ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling. Cell death & disease, 12(12), 1121.

Wu, P., Yuan, H., Ding, X., Chen, Q., Ge, W., Meng, L., ... & Lu, Z. (2020). LncRNA KCNK15-AS1 inhibits pancreatic cancer progression by promoting the expression of its binding protein ACTR3B.

Peng, J., Chen, X. L., Cheng, H. Z., Xu, Z. Y., Wang, H., Shi, Z. Z., ... & Peng, H. (2019). Silencing of KCNK15‑AS1 inhibits lung cancer cell proliferation via upregulation of miR‑202 and miR‑370. Oncology letters, 18(6), 5968-5976.

He, Y., Hu, H., Wang, Y., Yuan, H., Lu, Z., Wu, P., ... & Miao, Y. (2018). ALKBH5 inhibits pancreatic cancer motility by decreasing long non-coding RNA KCNK15-AS1 methylation. Cellular Physiology and Biochemistry, 48(2), 838-846.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Rabbit Anti-KCNK15 Recombinant Antibody (EG1764)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: