Rabbit Anti-KCNK17 Recombinant Antibody (EG1765) (CBMAB-EN2104-LY)

Name: Rabbit Anti-KCNK17 Recombinant Antibody (EG1765)
SKU: CBMAB-EN2104-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1765

Application

WB: 1:500~1:1000 ELISA: 1:20000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human KCNK17.

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Potassium Two Pore Domain Channel Subfamily K Member 17

Introduction

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Entrez Gene ID

89822

UniProt ID

Q96T54

Alternative Names

Potassium Two Pore Domain Channel Subfamily K Member 17; Potassium Channel, Two Pore Domain Subfamily K, Member 17; TWIK-Related Alkaline PH-Activated K(+) Channel 2; Acid-Sensitive Potassium Channel Protein TASK-4; TWIK-Related Acid-Sensitive K(+) Channel 4; 2P Domain Potassium Channel Talk-2; TALK-2;

Function

Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.

Biological Process

Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Stabilization of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-20
Helical: 21-43
Pore-forming: 106-124
Helical: 128-148
Cytoplasmic: 149-179
Helical: 180-200
Pore-forming: 211-230
Helical: 244-264
Cytoplasmic: 265-332

Dmitrzak-Weglarz, M., Szczepankiewicz, A., Chaberska, J., Kwiatkowska, K., Duda, J., Dziuda, S., ... & Pawlak, J. (2020). Transcripts of orphan nuclear receptor (NR4A1) & potassium channel (KCNK17) genes as new potential biomarkers for depression. Meta Gene, 26, 100786.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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