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Mouse Anti-KCNU1 Recombinant Antibody (CBXS-2348) (CBMAB-S5107-CQ)

This product is a mouse antibody that recognizes KCNU1. The antibody CBXS-2348 can be used for immunoassay techniques such as: ICC, WB.
See all KCNU1 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse
Clone
CBXS-2348
Antibody Isotype
IgG2b
Application
ICC, WB

Basic Information

Immunogen
Fusion protein aa 1052-1121 of mouse Slo3 (accession number AAB99742)
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.09% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
potassium channel, subfamily U, member 1
Entrez Gene ID
UniProt ID
Alternative Names
Kcnma3; Slo3; mSlo3
Function
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
Biological Process
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Reproductive processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-24
Helical: 25-45
Cytoplasmic: 46-101
Helical: 102-122
Extracellular: 123-138
Helical: 139-159
Cytoplasmic: 160-163
Helical: 164-184
Extracellular: 185-188
Helical: 189-209
Cytoplasmic: 210-226
Helical: 227-247
Extracellular: 248-259
Pore-forming: 260-282
Extracellular: 283-291
Helical: 292-312
Cytoplasmic: 313-1149
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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