Sign in or Register   Sign in or Register
  |  

Mouse Anti-KCTD15 Recombinant Antibody (PAT4C3AT) (CBMAB-K0631-LY)

This product is antibody recognizes KCTD15. The antibody PAT4C3AT immunoassay techniques such as: ELISA, WB, IF.
See all KCTD15 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
PAT4C3AT
Antibody Isotype
IgG
Application
ELISA, WB, IF

Basic Information

Immunogen
Anti-human KCTD15 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KCTD15 AA 1-234
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Potassium Channel Tetramerization Domain Containing 15
Introduction
During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain.
Entrez Gene ID
79047
UniProt ID
Q96SI1
Alternative Names
Potassium Channel Tetramerization Domain Containing 15; Potassium Channel Tetramerization Domain-Containing Protein 15; Potassium Channel Tetramerisation Domain Containing 15;
Function
During embryonic development, interferes with neural crest formation (By similarity).
Inhibits AP2 transcriptional activity by interaction with its activation domain.
Biological Process
Protein homooligomerizationIEA:InterPro
Cellular Location
Nucleus. In the brain, localizes to the arcuate hypothalamic nucleus, the ventromedial hypothalamic nucleus and the accumbens nucleus of the ventral striatum.

Coppola, L., Baselice, S., Messina, F., Giannatiempo, R., Farina, A., Vitagliano, L., ... & Salvatore, M. (2022). KCTD15 Is Overexpressed in her2+ Positive Breast Cancer Patients and Its Silencing Attenuates Proliferation in SKBR3 CELL LINE. Diagnostics, 12(3), 591.

Zhang, P., Fu, Y., Zhang, R., Shang, P., Zhang, H., & Zhang, B. (2022). Association of KCTD15 gene with fat deposition in pigs. Journal of Animal Physiology and Animal Nutrition, 106(3), 537-544.

Smaldone, G., Coppola, L., Pane, K., Franzese, M., Beneduce, G., Parasole, R., ... & Mirabelli, P. (2021). KCTD15 deregulation is associated with alterations of the NF-κB signaling in both pathological and physiological model systems. Scientific Reports, 11(1), 18237.

Xu, H., Shao, J., Fang, J., Yin, B., Zhang, L., Zhang, J., & Xia, G. (2021). miR-381 Targets KCTD15 to regulate bovine preadipocyte differentiation in vitro. Hormone and metabolic research, 53(01), 63-70.

Chambers, B. E., Clark, E. G., Gatz, A. E., & Wingert, R. A. (2020). Kctd15 regulates nephron segment development by repressing Tfap2a activity. Development, 147(23), dev191973.

Xu, J., Zhao, X., Yang, Y., Zhang, K., Wang, M., & Xu, Z. (2020). KCTD15 Gene Expression Regulates Adipocyte Differentiation and Is Associated with Obesity in Humans.

Spiombi, E., Angrisani, A., Fonte, S., De Feudis, G., Fabretti, F., Cucchi, D., ... & De Smaele, E. (2019). KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2. Oncogenesis, 8(11), 64.

Smaldone, G., Beneduce, G., Incoronato, M., Pane, K., Franzese, M., Coppola, L., ... & Salvatore, M. (2019). KCTD15 is overexpressed in human childhood B-cell acute lymphoid leukemia. Scientific Reports, 9(1), 20108.

Smaldone, G., Pirone, L., Capolupo, A., Vitagliano, L., Monti, M. C., Di Gaetano, S., & Pedone, E. (2018). The essential player in adipogenesis GRP78 is a novel KCTD15 interactor. International journal of biological macromolecules, 115, 469-475.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KCTD15 Recombinant Antibody (PAT4C3AT)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare