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Recombinant Mouse Anti-KIDINS220 Recombinant Antibody (1F8/3) (CBMAB-XB0686-YC)

Provided herein is a Mouse Recombinant Antibody against Kinase D Interacting Substrate 220. The antibody can be used for immunoassay techniques, such as ELISA, IHC, IP, WB.
See all KIDINS220 antibodies

Summary

Host Animal
Mouse
Specificity
Rat
Clone
1F8/3
Antibody Isotype
IgG1
Application
ELISA, IHC, IP, WB

Basic Information

Immunogen
Recombinant GST-Kidins220/ARMS (last 347 amino acids at the carboxy terminus) fusion protein.
Specificity
Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Kinase D Interacting Substrate 220
Introduction
KIDINS220 is a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity.
Entrez Gene ID
116478
UniProt ID
Q9EQG6
Alternative Names
Kinase D Interacting Substrate 220; Ankyrin Repeat-Rich Membrane-Spanning Protein; Kinase D-Interacting Substrate 220kDa; ARMS; Kinase D-Interacting Substrate Of 220 KDa; KIAA1250; SINO;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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