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Mouse Anti-KIF26A Recombinant Antibody (3C10) (CBMAB-K0872-LY)

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Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
3C10
Application
WB
Immunogen
KIF26A (AAH09415, 1 a.a. ~ 204 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Kinesin Family Member 26A
Introduction
Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity).
Entrez Gene ID
26153
UniProt ID
Q9ULI4
Alternative Names
Kinesin Family Member 26A; KIAA1236;
Function
Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity).
Biological Process
Enteric nervous system developmentISS:UniProtKB
Negative regulation of signal transductionISS:UniProtKB
Regulation of cell growth by extracellular stimulusISS:UniProtKB
Cellular Location
Cytoplasm, cytoskeleton

Ma, R. R., Zhang, H., Chen, H. F., Zhang, G. H., Tian, Y. R., & Gao, P. (2021). MiR-19a/miR-96-mediated low expression of KIF26A suppresses metastasis by regulating FAK pathway in gastric cancer. Oncogene, 40(14), 2524-2538.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

KIF26A Matched Antibody Pair (663) (CAT#: APMAB-663LY)

Related Products

KIF26A Matched Antibody Pair (663) (CAT#: APMAB-663LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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