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Rabbit Anti-KLC3 Recombinant Antibody (CBLY1-106) (CBMAB-K1031-LY)

This product is antibody recognizes KLC3. The antibody CBLY1-106 immunoassay techniques such as: WB, IHC-P, IP, FC, ICC/IF.
See all KLC3 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Human
Clone
CBLY1-106
Antibody Isotype
IgG
Application
WB, IHC-P, IP, FC, ICC/IF

Basic Information

Specificity
Mouse, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.098 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Kinesin Light Chain 3
Introduction
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human147700
Mouse232943
UniProt ID
HumanQ6P597
MouseQ91W40
Function
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa (By similarity).
May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece (By similarity).
Biological Process
Axo-dendritic transportIEA:Ensembl
Sperm mitochondrial sheath assemblyISS:UniProtKB
Spermatid developmentISS:UniProtKB
SpermatogenesisISS:UniProtKB
Cellular Location
Cytoplasm, cytoskeleton; Mitochondrion. In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria. Also localizes to the manchette in elongating spermatids.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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