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Mouse Anti-KLF16 Antibody (1E9) (CBMAB-0599-YC)

Provided herein are mouse monoclonal antibodies against Human KLF16. The antibody clone 1E9 can be used for immunoassay techniques, such as IP, WB and MA.
See all KLF16 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1E9
Antibody Isotype
IgG1
Application
IP, WB, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
KLF16
Introduction
KLF16 (kruppel like factor 16) is a protein that has transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is KLF14.
Entrez Gene ID
83855
UniProt ID
Q9BXK1
Alternative Names
BTEB4; DRRF; NSLP2
Function
Transcription factor that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences. Modulates dopaminergic transmission in the brain (By similarity).
Biological Process
Dopamine receptor signaling pathwayIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus

Yang, Z., Wang, Y. X., Wen, J. K., Gao, H. T., Han, Z. W., Qi, J. C., ... & Qu, C. B. (2023). SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm. Cell Death & Disease, 14(1), 26.

Mi, W., Zheng, Z., Lu, J. D., Duan, S. Q., Zhang, J., Zhang, H. Q., ... & Li, F. (2022). KLF16 promotes pancreatic adenocarcinoma cell proliferation and migration by positively regulating SMAD6. World Journal of Gastrointestinal Oncology, 14(11), 2157.

Ye, L., Liu, R., Lin, P., & Wang, W. (2022). Krüppel-like transcription factor 16 transcriptional up-regulation of cellular retinoic acid-binding proteins-2 promotes the invasion and migration and inhibits apoptosis of retinoblastoma cells by regulating integrin-β1/focal adhesion kinase/extracellular signal-regulated kinase pathway. Bioengineered, 13(2), 3694-3706.

Li, L., Zhang, X., Li, Y., Xiao, B., Pei, S., Jiang, H., & Zhang, X. (2022). Transcription factor KLF16 activates MAGT1 to regulate the tumorigenesis and progression of breast cancer. International Journal of Molecular Medicine, 50(3), 1-12.

Ma, X. D., Xu, S. D., Hao, S. H., Han, K., Chen, J. W., Ling, H., ... & Wang, F. W. (2022). KLF16 enhances stress tolerance of colorectal carcinomas by modulating nucleolar homeostasis and translational reprogramming. Molecular Therapy, 30(8), 2828-2843.

Sun, N., Shen, C., Zhang, L., Wu, X., Yu, Y., Yang, X., ... & Gao, Y. (2021). Hepatic Krüppel-like factor 16 (KLF16) targets PPARα to improve steatohepatitis and insulin resistance. Gut, 70(11), 2183-2195.

Sun, D. P., Tian, Y. F., Lin, C. C., Hung, S. T., Uen, Y. H., Hseu, Y. C., ... & Lin, K. Y. (2021). A novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of gastric cancer through regulating the Notch pathway. American Journal of Cancer Research, 11(6), 2717.

Bang, S., Li, J., Zhang, M., Cui, R., Wu, X., Xin, Z., ... & Zhang, H. (2020). The clinical relevance and function of Krüppel-like factor 16 in breast cancer. Cancer Management and Research, 6373-6383.

Zhang, J., Yu, W., Wang, X., Hu, B., Wu, D., & Shi, G. (2020). KLF16 affects the MYC signature and tumor growth in prostate cancer. OncoTargets and therapy, 1303-1310.

Zhang, L., Cao, Y., Wei, M., Jiang, X., & Jia, D. (2018). Long noncoding RNA‐RNCR3 overexpression deleteriously affects the growth of glioblastoma cells through miR‐185‐5p/Krüppel‐like factor 16 axis. Journal of cellular biochemistry, 119(11), 9081-9089.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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