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Mouse Anti-KLHL31 Recombinant Antibody (CBLY1-118) (CBMAB-K1198-LY)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBLY1-118
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Kelch Like Family Member 31
Introduction
Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).
Entrez Gene ID
Human401265
Mouse244923
Rat315833
UniProt ID
HumanQ9H511
MouseQ8BWA5
RatD3ZLT6
Function
Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).
Biological Process
Negative regulation of JNK cascadeManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of protein phosphorylationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm; Nucleus
PTM
N-terminus is methylated by METTL11A/NTM1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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