Sign in or Register   Sign in or Register
  |  

Mouse Anti-KLK12 Recombinant Antibody (364926) (CBMAB-K1215-LY)

This product is antibody recognizes KLK12. The antibody 364926 immunoassay techniques such as: WB.
See all KLK12 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
364926
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Kallikrein 12, Ala18-Asn248
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Kallikrein Related Peptidase 12
Introduction
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Entrez Gene ID
43849
UniProt ID
Q9UKR0
Alternative Names
Kallikrein Related Peptidase 12; Kallikrein-Like Protein 5; KLK-L5; KLKL5; Kallikrein 12; Kallikrein-12; EC 3.4.21.-; EC 3.4.21;
Biological Process
ProteolysisManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Secreted

Sato, A., Takagi, K., Yoshimura, A., Tsukamoto, W., Yamaguchi-Tanaka, M., Miki, Y., ... & Suzuki, T. (2023). Kallikrein-Related Peptidase 12 (KLK12) in Breast Cancer as a Favorable Prognostic Marker. International journal of molecular sciences, 24(9), 8419.

Lavergne, M., Guillon-Munos, A., Bonda, W. L. M., Attucci, S., Kryza, T., Barascu, A., ... & Reverdiau, P. (2021). Tissue factor pathway inhibitor 2 is a potent kallikrein-related protease 12 inhibitor. Biological Chemistry, 402(10), 1257-1268.

Gong, W., Liu, Y., Preis, S., Geng, X., Petit-Courty, A., Kiechle, M., ... & Magdolen, V. (2020). Prognostic value of kallikrein-related peptidase 12 (KLK12) mRNA expression in triple-negative breast cancer patients. Molecular Medicine, 26, 1-9.

Sabir, N., Hussain, T., Liao, Y., Wang, J., Song, Y., Shahid, M., ... & Zhou, X. (2019). Kallikrein 12 regulates innate resistance of murine macrophages against Mycobacterium bovis infection by modulating autophagy and apoptosis. Cells, 8(5), 415.

Adamopoulos, P. G., Kontos, C. K., & Scorilas, A. (2018). Novel splice variants of the human kallikrein-related peptidases 11 (KLK11) and 12 (KLK12), unraveled by next-generation sequencing technology. Biological Chemistry, 399(9), 1065-1071.

Kryza, T., Parent, C., Pardessus, J., Petit, A., Burlaud-Gaillard, J., Reverdiau, P., ... & Heuzé-Vourc’h, N. (2018). Human kallikrein-related peptidase 12 stimulates endothelial cell migration by remodeling the fibronectin matrix. Scientific Reports, 8(1), 6331.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KLK12 Recombinant Antibody (364926)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare