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Mouse Anti-KLK13 Recombinant Antibody (10H10A2C4) (CBMAB-K1219-LY)

This product is antibody recognizes KLK13. The antibody 10H10A2C4 immunoassay techniques such as: ELISA.
See all KLK13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
10H10A2C4
Antibody Isotype
IgG2a
Application
ELISA

Basic Information

Immunogen
Recombinant Human KLK13 protein
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
kallikrein-related peptidase 13
Introduction
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. [provided by RefSeq, Jan 2017]
Entrez Gene ID
26085
UniProt ID
Q9UKR3
Alternative Names
Kallikrein Related Peptidase 13; Kallikrein-Like Protein 4; KLK-L4; KLKL4; Kallikrein-Like Gene 4; Kallikrein 13; Kallikrein-13; EC 3.4.21.-; EC 3.4.21;
Biological Process
Protein processingIEA:Ensembl
Proteolysis1 PublicationNAS:UniProtKB
Cellular Location
Secreted

Sumiya, R., Yamada, K., Hagiwara, T., Nagasaka, S., Miyazaki, H., Igari, T., & Kawamura, Y. I. (2023). Kallikrein-related peptidase 13 expression and clinicopathological features in lung squamous cell carcinoma. Molecular and Clinical Oncology, 19(2), 1-7.

Shimomura, A., Hagiwara, T., Yamada, K., Yokoi, C., Terayama, M., Nohara, K., ... & Kawamura, Y. I. (2023). Induction of kallikrein-related peptidase 13 and TET2/3 by anticancer drugs and poor prognosis of patients with esophageal squamous cell carcinoma after preoperative treatment. Annals of Surgical Oncology, 1-11.

Gruba, N., Rachubik, P., Piwkowska, A., & Lesner, A. (2021). Analysis of urinary kallikrein-related peptidase 13 for monitoring bladder cancer. Biomarkers, 26(8), 770-779.

Milewska, A., Falkowski, K., Kalinska, M., Bielecka, E., Naskalska, A., Mak, P., ... & Pyrc, K. (2020). Kallikrein 13: a new player in coronaviral infections. biorxiv, 2020-03.

Milewska, A., Falkowski, K., Kulczycka, M., Bielecka, E., Naskalska, A., Mak, P., ... & Pyrc, K. (2020). Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1. Science signaling, 13(659), eaba9902.

Nohara, K., Yamada, K., Yamada, L., Hagiwara, T., Igari, T., Yokoi, C., ... & Kawamura, Y. I. (2018). Expression of kallikrein-related peptidase 13 is associated with poor prognosis in esophageal squamous cell carcinoma. General thoracic and cardiovascular surgery, 66, 351-357.

Gruba, N., Bielecka, E., Wysocka, M., Wojtysiak, A., Brzezińska-Bodal, M., Sychowska, K., ... & Lesner, A. (2019). Development of chemical tools to monitor human kallikrein 13 (KLK13) activity. International journal of molecular sciences, 20(7), 1557.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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