Recombinant Rat Anti-Klrb1b Recombinant Antibody (2D9) (CBMAB-XB0698-YC)

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Basic Information

Host Animal
Rat
Clone
2D9
Application
FC
Immunogen
YB2/0 rat plasmacytoma cells transfected with NKRP1
Specificity
Rat, Mouse
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Killer Cell Lectin-like Receptor, Subfamily B Member 1B
Introduction
Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent "missing-self" recognition of allografts, tumor cells and virus-infected cells.
Entrez Gene ID
Rat25192
Mouse80782
UniProt ID
RatQ5NKN4
MouseP27812
Alternative Names
Ly55b; Ly55d; Klrb1d; Nkrp1b; Nkrp1d; ly-55b; ly-55d; NKR-P1B; NKR-P1D; Nkrp1-b
Function
Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells.
Biological Process
Negative regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Membrane
Topology
Cytoplasmic: 1-43
Helical: 44-63
Extracellular: 64-223
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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