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Mouse Anti-KLRC4 Recombinant Antibody (1D10) (CBMAB-K1407-LY)

This product is antibody recognizes KLRC4. The antibody 1D10 immunoassay techniques such as: ELISA, WB.
See all KLRC4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D10
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
killer cell lectin-like receptor subfamily C, member 4
Introduction
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member. [provided by RefSeq, Dec 2010]
Entrez Gene ID
8302
UniProt ID
O43908
Alternative Names
Killer Cell Lectin Like Receptor C4; Killer Cell Lectin-Like Receptor Subfamily C; Member 4; NKG2-F-Activating NK Receptor; NK Cell Receptor F; NKG2F; NKG2-F Type II Integral Membrane Protein; Natual Killer Cell Group 2-F; NKG2-F;
Function
May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells.
Biological Process
Positive regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIBA:GO_Central
Stimulatory C-type lectin receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-74
Helical: 75-95
Extracellular: 96-158
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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