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Mouse Anti-KRT15 Recombinant Antibody (60000000) (CBMAB-C1459-YY)

This product is mouse antibody that recognizes KRT15. The antibody 60000000 can be used for immunoassay techniques such as: ELISA, WB, IHC-P, IF, FC
See all KRT15 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
60000000
Antibody Isotype
IgG2a
Application
ELISA, WB, IHC-P, IF, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Ascites
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Keratin 15
Entrez Gene ID
3866
UniProt ID
P19012
Alternative Names
Cathepsin K; Cathepsin O2; EC 3.4.22.38; Cathepsin O; Cathepsin X; CTSO2; CTSO; Cathepsin K (Pycnodysostosis);
Biological Process
Epidermis developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytosol
Extracellular exosome
Intermediate filament

Zhu, W., Han, L., Wu, Y., Tong, L., He, L., Wang, Q., ... & Zhou, J. (2023). Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9. Respiratory Research, 24(1), 1-16.

Zhang, W., Chen, P., Li, Z., Zhang, R., & Zhang, J. (2023). Clinical implication of keratin-15 quantification for renal cell carcinoma management: its dysregulation and association with clinicopathologic characteristics and prognostication. The Tohoku Journal of Experimental Medicine, 260(2), 99-107.

Ievlev, V., Lynch, T. J., Freischlag, K. W., Gries, C. B., Shah, A., Pai, A. C., ... & Parekh, K. R. (2023). Krt14 and Krt15 differentially regulate regenerative properties and differentiation potential of airway basal cells. JCI insight, 8(2).

Yang, X., Liu, Z., Wang, X., Han, Z., Zhang, C., & Guo, L. (2023). Tumor keratin 15 expression links with less extent of invasion and better prognosis in papillary thyroid cancer patients receiving tumor resection. Irish Journal of Medical Science (1971-), 1-7.

Wang, J., & Zhu, G. (2023). Silencing of keratin 15 impairs viability and mobility while facilitating the doxorubicin chemosensitivity by inactivating the β‑catenin pathway in liver cancer. Oncology Letters, 26(4), 1-8.

Kohler, K. T., Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, K., Rønnov-Jessen, L., ... & Kim, J. (2022). Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature. NPJ Breast Cancer, 8(1), 81.

Zhong, P., Shu, R., Wu, H., Liu, Z., Shen, X., & Hu, Y. (2021). Low KRT15 expression is associated with poor prognosis in patients with breast invasive carcinoma. Experimental and Therapeutic Medicine, 21(4), 1-1.

Rao, X., Wang, J., Song, H. M., Deng, B., & Li, J. G. (2020). KRT15 overexpression predicts poor prognosis in colorectal cancer. Neoplasma, 67(2), 410-414.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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