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Mouse Anti-KRT7 Recombinant Antibody (CBYY-C2622) (CBMAB-C4063-YY)

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Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBYY-C2622
Application
IF, WB
Immunogen
Purified recombinant human Cytokeratin 7 protein fragments expressed in E.coli
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Affinity purified
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Keratin 7
Entrez Gene ID
3855
UniProt ID
P08729
Alternative Names
Melanoma Cell Adhesion Molecule; S-Endo 1 Endothelial-Associated Antigen; Melanoma-Associated Antigen MUC18; Cell Surface Glycoprotein P1H12; Melanoma-Associated Antigen A32; Gicerin;
Function
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Cellular Location
Cytoplasm
PTM
Arg-20 is dimethylated, probably to asymmetric dimethylarginine.

Zhao, Z., Meng, M., Yao, J., Zhou, H., Chen, Y., Liu, J., ... & Zhou, Q. (2023). The long non-coding RNA keratin-7 antisense acts as a new tumor suppressor to inhibit tumorigenesis and enhance apoptosis in lung and breast cancers. Cell Death & Disease, 14(4), 293.

Dariane, C., Clairefond, S., Péant, B., Communal, L., Thian, Z., Ouellet, V., ... & Saad, F. (2022). High Keratin-7 Expression in Benign Peri-Tumoral Prostatic Glands Is Predictive of Bone Metastasis Onset and Prostate Cancer-Specific Mortality. Cancers, 14(7), 1623.

Lin, M., Wang, J., Wang, S., & Huang, Y. (2022). Expression level of keratin 7 in epithelial ovarian cancer and malignant metastasis of benign epithelial ovarian tumors. Cellular and Molecular Biology, 68(2), 153-161.

Communal, L., Roy, N., Cahuzac, M., Rahimi, K., Köbel, M., Provencher, D. M., & Mes-Masson, A. M. (2021). A Keratin 7 and E-Cadherin Signature Is Highly Predictive of Tubo-Ovarian High-Grade Serous Carcinoma Prognosis. International Journal of Molecular Sciences, 22(10), 5325.

An, Q., Liu, T., Wang, M. Y., Yang, Y. J., Zhang, Z. D., Liu, Z. J., & Yang, B. (2021). KRT7 promotes epithelial‑mesenchymal transition in ovarian cancer via the TGF‑β/Smad2/3 signaling pathway. Oncology reports, 45(2), 481-492.

Li, Y., Su, Z., Wei, B., & Liang, Z. (2021). KRT7 overexpression is associated with poor prognosis and immune cell infiltration in patients with pancreatic adenocarcinoma. International Journal of General Medicine, 2677-2694.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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