Mouse Anti-KRT72 Recombinant Antibody (0.N.347) (CBMAB-K1924-LY)

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Basic Information

Host Animal
Mouse
Clone
0.N.347
Application
IHC, ELISA
Immunogen
Synthetic peptide corresponding to GSSTIKYTTTS from the C-terminus of human keratin 6. Cellular Localization: Cytoplasmic. Epitope: C-terminal
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Keratin 72
Introduction
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
Human140807
Mouse105866
UniProt ID
HumanQ14CN4
MouseQ6IME9
Alternative Names
KRT6; K6irs; K6IRS2; KRT6IRS2
Function
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).
Cellular Location
Cytosol
Extracellular exosome
Keratin filament
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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