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Mouse Anti-L-3-nitrotyrosine Recombinant Antibody (HM.11) (CBMAB-N0375-WJ)

This product is a Mouse antibody that recognizes L-3-nitrotyrosine. The antibody HM.11 can be used for immunoassay techniques such as: WB, ELISA, IHC-P, IHC-Fr.
See all L-3-nitrotyrosine antibodies
Published Data
Fig.1 Representative images of immunostaining (dark brown) for each oxidative damage marker in interstitial cells: protein oxidation (NTY) in the ovaries of the NC group.
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Fig.2 Representative immunofluorescence showing nitrotyrosine in AVF, matched at postoperative days 3.
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Fig.3 Western blot of 3-nitrotyrosine. GAPDH was used as a loading control.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
HM.11
Antibody Isotype
IgG2b
Application
WB, ELISA, IHC-P, IHC-Fr

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
L-3-nitrotyrosine
Introduction
Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species such as peroxynitrite anion and nitrogen dioxide. Nitrotyrosine is identified as an indicator or marker of cell damage, inflammation as well as NO (nitric oxide) production. Nitrotyrosine is formed in the presence of the active metabolite NO. Generally in many disease states, oxidative stress increases the production of superoxide (O2−) and NO forming peroxynitrite (ONOO−) a destructive free radical oxidant.
Alternative Names
L-3-nitrotyrosine, 3-Nitrotyrosine, 7COY1HA6HK, 621-44-3, Nitrotyrosine
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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