Mouse Anti-L3MBTL4 Recombinant Antibody (1B9-1C12) (CBMAB-L0453-YJ)

Name: Mouse Anti-L3MBTL4 Recombinant Antibody (1B9-1C12)
SKU: CBMAB-L0453-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1B9-1C12

Application

Immunogen

L3MBTL4 (AAH39316, 1 a.a. ~ 535 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-535

More Infomation

Target

Full Name

L3MBTL4

Introduction

Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity. An important paralog of this gene is L3MBTL3. L3MBTL4 is a putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably by a modification of chromatin, rendering it heritably changed in its expressibility (By similarity).

Entrez Gene ID

91133

UniProt ID

Q8NA19

Function

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity).

Biological Process

Chromatin organizationIEA:UniProtKB-KW
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Ma, L., Liu, Y., Xu, F., Shen, R., Wang, M., Zhang, Y., ... & Zheng, G. (2023). IL-27-induced, MSC-derived Exosomes Promote MMP3 Expression Through the miR-206/L3MBTL4 Axis in Synovial Fibroblasts. Alternative Therapies in Health and Medicine, AT8854-AT8854.

Hu, C., Zuo, K., Li, K., Gao, Y., Chen, M., Hu, R., ... & Li, J. (2020). p38/JNK is required for the proliferation and phenotype changes of vascular smooth muscle cells induced by L3MBTL4 in essential hypertension. International Journal of Hypertension, 2020.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

L3MBTL4 Matched Antibody Pair (677) (CAT#: APMAB-677LY)

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L3MBTL4 Matched Antibody Pair (677) (CAT#: APMAB-677LY)

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Mouse Anti-L3MBTL4 Recombinant Antibody (CBYJL-1041) (CAT#: CBMAB-L0455-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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