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Mouse Anti-LGALS13 Recombinant Antibody (PP13/1161) (CBMAB-L1247-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Galectin 13 (LGALS13). The antibody can be used for immunoassay techniques, such as WB, IHC-P, IF, ICC, FC.
See all LGALS13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
PP13/1161
Antibody Isotype
IgG2b, κ
Application
WB, IHC-P, IF, ICC, FC

Basic Information

Immunogen
Recombinant human Galectin-13 protein fragment (aa 23-134) (exact sequence is proprietary).
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1 mM PBS, 0.05% BSA
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 23-134

Target

Full Name
Galectin 13
Introduction
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. LGALS13 has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. LGALS13 has structural similarity to several members of the beta-galactoside-binding S-type lectin family. Diseases associated with LGALS13 include Severe Pre-Eclampsia and Pre-Eclampsia. Among its related pathways are Integrated Breast Cancer Pathway. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and lysophospholipase activity.An important paralog of this gene is LGALS16.
Entrez Gene ID
29124
UniProt ID
Q9UHV8
Alternative Names
GAL13; PLAC8; PP13
Function
Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis (PubMed:10527825, PubMed:19497882).
Has hemagglutinating activity towards chicken erythrocytes (PubMed:29343868).
Biological Process
Apoptotic processIEA:UniProtKB-KW
Phospholipid metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of T cell apoptotic processIEA:InterPro
Cellular Location
Cytoplasm
Nucleus matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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