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Mouse Anti-LGALS3BP Recombinant Antibody (CF268) (CBMAB-FT226LY)

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Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CF268
Application
ELISA, WB, IHC, IP, IF
Immunogen
lectin, galactoside-binding, soluble, 3 binding protein
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
LGALS3BP
Entrez Gene ID
3959
UniProt ID
Q08380
Alternative Names
90K, BTBD17B, Galectin 3 binding protein, LGALS3BP, M2BP, Mac 2 binding protein, MAC 2 BP, MAC2BP, Tumor associated antigen 90K
Function
Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
Biological Process
Cell adhesionIEA:UniProtKB-KW
Cellular defense responseManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
Secreted, extracellular space, extracellular matrix

Zhao, C., Liu, Y., Meng, J., Wang, X., Liu, X., Li, W., ... & Hou, S. (2022). Lgals3bp in Microglia Promotes Retinal Angiogenesis through Pi3k/Akt Pathway During Hypoxia. Investigative Ophthalmology & Visual Science, 63(8), 25-25.

Song, Y., Wang, M., Tong, H., Tan, Y., Hu, X., Wang, K., & Wan, X. (2021). Plasma exosomes from endometrial cancer patients contain LGALS3BP to promote endometrial cancer progression. Oncogene, 40(3), 633-646.

Kyrousi, C., O’neill, A. C., Brazovskaja, A., He, Z., Kielkowski, P., Coquand, L., ... & Cappello, S. (2021). Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity. Nature Communications, 12(1), 6298.

Luo, M., Zhang, Q., Hu, Y., Sun, C., Sheng, Y., & Deng, C. (2021). Lgals3bp: A potential plasma biomarker associated with diagnosis and prognosis in patients with sepsis. Infection and Drug Resistance, 2863-2871.

Cho, S. H., Shim, H. J., Park, M. R., Choi, J. N., Akanda, M. R., Hwang, J. E., ... & Chung, I. J. (2021). Lgals3bp suppresses colon inflammation and tumorigenesis through the downregulation of TAK1-NF-κB signaling. Cell death discovery, 7(1), 65.

Costa, J., Pronto-Laborinho, A., Pinto, S., Gromicho, M., Bonucci, S., Tranfield, E., ... & de Carvalho, M. (2020). Investigating LGALS3BP/90 K glycoprotein in the cerebrospinal fluid of patients with neurological diseases. Scientific reports, 10(1), 5649.

Kimura, R., Yoshimaru, T., Matsushita, Y., Matsuo, T., Ono, M., Park, J. H., ... & Katagiri, T. (2020). The GALNT6‑LGALS3BP axis promotes breast cancer cell growth. International Journal of Oncology, 56(2), 581-595.

Zhang, X., Ding, H., Lu, Z., Ding, L., Song, Y., Jing, Y., ... & Ni, Y. (2019). Increased LGALS3BP promotes proliferation and migration of oral squamous cell carcinoma via PI3K/AKT pathway. Cellular Signalling, 63, 109359.

Xu, G., Xia, Z., Deng, F., Liu, L., Wang, Q., Yu, Y., ... & Liu, S. (2019). Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS pathogens, 15(8), e1008002.

Lodermeyer, V., Ssebyatika, G., Passos, V., Ponnurangam, A., Malassa, A., Ewald, E., ... & Goffinet, C. (2018). The antiviral activity of the cellular glycoprotein LGALS3BP/90K is species specific. Journal of virology, 92(14), 10-1128.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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