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Mouse Anti-LGI2 Recombinant Antibody (CBYJL-1539) (CBMAB-L1318-YJ)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-1539
Antibody Isotype
IgG2b
Application
WB, ICC

Basic Information

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human LGI2, Gln29-Ser276, Accession # Q8N0V4.
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 29-276

Target

Full Name
leucine rich repeat LGI family member 2
Introduction
Diseases associated with LGI2 include Deafness, Autosomal Recessive 98. Among its related pathways are LGI-ADAM interactions and Developmental Biology. An important paralog of this gene is LGI1.
Entrez Gene ID
UniProt ID
Function
Required for the development of soma-targeting inhibitory GABAergic synapses made by parvalbumin-positive basket cells.
Biological Process
Inhibitory synapse assemblyISS:UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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