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Mouse Anti-LILRA1 Recombinant Antibody (CBYJL-1666) (CBMAB-L1537-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Leukocyte Immunoglobulin Like Receptor A1 (LILRA1). The antibody can be used for immunoassay techniques, such as FC.
See all LILRA1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-1666
Antibody Isotype
IgG2b
Application
FC

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LILRA1, Pro17-Asn461, Accession # O75019.
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, BSA
Preservative
Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Leukocyte Immunoglobulin Like Receptor A1
Introduction
LILRA1 is an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. LILRA1 is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Osteoclast differentiation. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity and antigen binding. An important paralog of this gene is LILRA2.
Entrez Gene ID
11024
UniProt ID
O75019
Alternative Names
LIR6; CD85I; LIR-6
Function
May act as receptor for class I MHC antigens.
Biological Process
Adaptive immune responseIEA:UniProtKB-KW
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Defense responseManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 17-461
Helical: 462-482
Cytoplasmic: 483-489
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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