Mouse Anti-LILRA1 Recombinant Antibody (CBYJL-1666) (CBMAB-L1537-YJ)

Name: Mouse Anti-LILRA1 Recombinant Antibody (CBYJL-1666)
SKU: CBMAB-L1537-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYJL-1666

Application

Immunogen

Mouse myeloma cell line NS0-derived recombinant human LILRA1, Pro17-Asn461, Accession # O75019.

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, BSA

Preservative

Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Leukocyte Immunoglobulin Like Receptor A1

Introduction

LILRA1 is an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. LILRA1 is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Osteoclast differentiation. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity and antigen binding. An important paralog of this gene is LILRA2.

Entrez Gene ID

11024

UniProt ID

O75019

Alternative Names

LIR6; CD85I; LIR-6

Function

May act as receptor for class I MHC antigens.

Biological Process

Adaptive immune responseIEA:UniProtKB-KW
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Defense responseManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Membrane

Topology

Extracellular: 17-461
Helical: 462-482
Cytoplasmic: 483-489

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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