Mouse Anti-LMO4 Recombinant Antibody (CBYCL-400) (CBMAB-L0301-YC)

Name: Mouse Anti-LMO4 Recombinant Antibody (CBYCL-400)
SKU: CBMAB-L0301-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYCL-400

Application

ELISA, IHC-P

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

LIM domain only 4

Introduction

LMO4 is a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene.

Entrez Gene ID

8543

UniProt ID

P61968

Alternative Names

A730077C12Rik; Crp3; Etohi4

Function

Probable transcriptional factor.

Biological Process

Negative regulation of protein-containing complex assemblyIEA:Ensembl
Neural tube closureISS:UniProtKB
Positive regulation of kinase activityISS:UniProtKB
Positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Regulation of cell activationIEA:Ensembl
Regulation of cell fate specificationIEA:Ensembl
Regulation of cell migrationISS:UniProtKB
Spinal cord association neuron differentiationIEA:Ensembl
Spinal cord motor neuron differentiationIEA:Ensembl
Thymus developmentIEA:Ensembl
Ventral spinal cord interneuron differentiationIEA:Ensembl
Ventricular septum developmentIEA:Ensembl

Cellular Location

Cell leading edge
RNA polymerase II transcription regulator complex
Transcription regulator complex

Muradova, G., & Zulfugarov, I. (2023). Transcriptional regulator LIM-domain-only 4 (LMO4) protein: The role in human immune system.

Rosati, R., Shahab, M., Ramkumar, V., & Jamesdaniel, S. (2021). Lmo4 deficiency enhances susceptibility to cisplatin-induced cochlear apoptosis and hearing loss. Molecular neurobiology, 58, 2019-2029.

Xiong, X., Feng, Y., Li, L., Yao, J., Zhou, M., Zhao, P., ... & Yuan, L. (2020). Long non‑coding RNA SNHG1 promotes breast cancer progression by regulation of LMO4. Oncology reports, 43(5), 1503-1515.

Wang, N., Dong, Q., & Zhou, X. N. (2019). LMO4 promotes the invasion and proliferation of gastric cancer by activating PI3K-Akt-mTOR signaling. American Journal of Translational Research, 11(10), 6534.

McClymont, G. C. (2018). Methods to identify novel α-helical peptides that bind to LMO4 (Doctoral dissertation).

Huang, Y., Hill, J., Yatteau, A., Wong, L., Jiang, T., Petrovic, J., ... & Wu, D. K. (2018). Reciprocal negative regulation between Lmx1a and Lmo4 is required for inner ear formation. Journal of Neuroscience, 38(23), 5429-5440.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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