Mouse Anti-LPPR4 Recombinant Antibody (CBYJL-1945) (CBMAB-L2003-YJ)

Name: Mouse Anti-LPPR4 Recombinant Antibody (CBYJL-1945)
SKU: CBMAB-L2003-YJ
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYJL-1945

Antibody Isotype

IgG

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Phospholipid Phosphatase Related 4

Introduction

LPPR4 belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. LPPR4 is specifically expressed in neurons. LPPR4 is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Entrez Gene ID

9890

UniProt ID

Q7Z2D5

Alternative Names

LPR4; PHP1; PRG1; LPPR4; PRG-1; phospholipid phosphatase-related protein type 4; brain-specific phosphatidic acid phosphatase-like protein 1; lipid phosphate phosphatase-related protein type 4; plasticity related gene 1; plasticity-related gene 1 protein; EC 3.1.3.4

Biological Process

AxonogenesisIEA:InterPro
Phospholipid metabolic processIEA:InterPro

More Infomation

References

Wu, Y., Zhang, W., Wang, Y., Lu, Q., Zhou, J., Chen, Z., ... & Loor, J. J. (2023). Molecular mechanisms in the miR-33a/LPPR4 pathway regulating unsaturated fatty acid synthesis in bovine mammary epithelial cells. Animal Biotechnology, 34(7), 2636-2648.

Zang, D., Zhang, C., Li, C., Fan, Y., Li, Z., Hou, K., ... & Qu, X. (2020). LPPR4 promotes peritoneal metastasis via Sp1/integrin α/FAK signaling in gastric cancer. American journal of cancer research, 10(3), 1026.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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