Mouse Anti-LRFN4 Recombinant Antibody (CBXS-1863) (CBMAB-S4662-CQ)

Name: Mouse Anti-LRFN4 Recombinant Antibody (CBXS-1863)
SKU: CBMAB-S4662-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-1863

Application

IHC

Immunogen

CHO-derived recombinant human SALM3/LRFN4, Cys17-Leu518, Accession # Q6PJG9

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Concentration

LYOPH

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

leucine rich repeat and fibronectin type III domain containing 4

Entrez Gene ID

78999

UniProt ID

Q6PJG9

Alternative Names

FIGLER6; SALM3; SALM3.

Function

Promotes neurite outgrowth in hippocampal neurons. May play a role in redistributing DLG4 to the cell periphery (By similarity).

Biological Process

Regulation of postsynaptic density assemblyManual Assertion Based On ExperimentIBA:GO_Central
Regulation of presynapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Synaptic membrane adhesionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane

Topology

Extracellular: 17-518
Helical: 519-539
Cytoplasmic: 540-635

PTM

Glycosylated.

Gu, Y. H., Wang, J., Lu, W. C., Cheng, Y., Tao, R., Zhang, S. J., ... & Xin, W. J. (2023). POU2F1/DNMT3a Pathway Participates in Neuropathic Pain by Hypermethylation-Mediated LRFN4 Downregulation Following Oxaliplatin Treatment. Neurochemical Research, 48(12), 3652-3664.

Zhu, Z., Peng, L., Luo, H., Jiang, Y., Yang, M., Gu, H., & Wang, Y. (2022). Expression and relationship with immunity of LRFN4 in lung adenocarcinoma: Based on bioinformatics analysis. medRxiv, 2022-11.

Han, S., Zhu, W., Yang, W., Guan, Q., Chen, C., He, Q., ... & Tian, J. (2021). A prognostic signature constructed by CTHRC1 and LRFN4 in stomach adenocarcinoma. Frontiers in genetics, 12, 646818.

Zheng, F., Zhai, X. L., Wang, W. J., Guo, K. P., Xiao, C. C., & Ni, Q. C. (2020). Expression and clinical significance of LRFN4 in colorectal cancer tissue. Zhonghua yi xue za zhi, 100(22), 1745-1749.

Han, S., Zhu, W., Guan, Q., Zhong, Z., Zhao, R., Xiong, H., ... & Tian, J. (2020). A prognostic model constructed by CTHRC1 and LRFN4 in Stomach adenocarcinoma by Bioinformatics Analysis.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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